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What is the role of testosterone in muscle development

Testosterone plays a crucial role in muscle development. It promotes muscle growth through several mechanisms.


Firstly, testosterone binds to androgen receptors on muscle cells, initiating a cascade of cellular events that lead to increased protein synthesis. This results in the formation of new muscle fibers and the enhancement of muscle size and strength.


Additionally, testosterone inhibits the action of myostatin, a protein that limits muscle growth. By reducing myostatin's effects, testosterone further supports muscle hypertrophy.


Moreover, testosterone enhances muscle repair and recovery after exercise, contributing to overall muscle health.


References:

  1. Griggs, R. C., Kingston, W., Jozefowicz, R. F., Herr, B. E., Forbes, G., & Halliday, D. (1989). Effect of testosterone on muscle mass and muscle protein synthesis. Journal of Applied Physiology, 66(1), 498-503. doi: 10.1152/jappl.1989.66.1.498

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