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What is the impact of testosterone on hair growth?

Testosterone significantly influences hair growth, particularly in males. The conversion of testosterone to its more potent form, dihydrotestosterone (DHT), by the enzyme 5-alpha-reductase plays a crucial role.


DHT binds to hair follicles, causing them to shrink over time. While DHT is essential for the growth of facial and body hair during puberty, an excessive amount can contribute to male pattern baldness. Androgen receptors in hair follicles are more sensitive to DHT as men age, leading to the miniaturization of hair follicles and eventual hair loss.


Genetics also play a role in determining an individual's sensitivity to DHT.

References:

  1. Montgomery, B. J. (2001). Hair: Its structure and response to cosmetic preparations. Clinics in Dermatology, 19(2), 213-225. doi: 10.1016/s0738-081x(00)00175-2

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